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No adverse effects have been found in test subjects being administered native IGF-1 for periods between two to twelve weeks [18, 19]
The long-term use of GLP-1 should be decided case by case under medical guidance only
In studies involving patients with overweight or obesity, participants experienced an average weight loss of 5.9% after 3 months and 10.9% after 6 months
315 The expression levels of GLP-1R, PKA/CREB signaling pathway components, and inflammation-related proteins (such as TNF-, IL-1, and IL-6) in the rat knee cartilage tissue were measured using Western blot and immunoprecipitation techniques
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