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The 2017 Neelakantan paper in Biochemistry characterised a fluorescent assay for direct real-time monitoring of NNMT enzymatic activity, providing the analytical foundation for inhibitor screening including 5-Amino-1MQ (PMID 28121423)
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207.3 PROtocols matter: A systematised evaluation of adherence to Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) patient-reported outcome guidelines in interventional paediatric oncology trials Denise Connolly 1 , Sarah Cohen-Gogo 1 , Sharon De Graves 2 1 The Hospital for Sick Children, Toronto, Ontario, Canada, 2 University of Melbourne, Melbourne, Australia Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :207.3 Aims Despite increasing recognition of their importance, patient-reported outcomes (PROs) remain poorly implemented in interventional paediatric oncology trials
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![PDF] Kinetic Mechanism and Molecular Properties of Glutathione Reductase](https://figures.semanticscholar.org/86e0c3c8c13578b78a6eae1f4d6a473e325ce3d3/4-Figure1-1.png)
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