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In silico examination of CBS promoter by Jaspar software 38 predicted one putative antioxidant response element (ARE) ~ 5 kb upstream of the transcription start site, which is highly associated with H3K4Me1, H3K4Me2, H3K4Me3, and H3K9Ac histone marks (Supplementary Fig
The regulatory role of ROS in cell survival and death provides promising therapeutic targets
Nevertheless, the CD44v9/xCT pathway or Nrf2 inhibitors have limited therapeutic effects
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