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In extreme cases, people with pernicious anemia or a related condition known as vitamin B12 deficiency myelopathy can develop nerve damage related to vitamin B12 deficiency
110 Berberine can also increase GATA-2 and GATA-3 mRNA and protein expression in 3T3-L1 cells and reduce expression of PPAR and C/EBP mRNA and weight gain in high-fat diet-induced obese mice
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In the single source study, AHK-Cu stimulated the proliferation of cultured human DPCs and the elongation of isolated human hair follicles at very low concentrations (1010 M), raised the Bcl-2/Bax ratio and lowered cleaved caspase-3 and PARP though the drop in apoptotic-cell count itself was not statistically significant [1]
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