Antioxidant-rich foods such as berries, citrus fruits, and green leafy vegetables can synergistically work with Glutathione to combat oxidative stress
Given the brains unique susceptibility to proteotoxic stress, owing to its post-mitotic neuronal population, high metabolic demand, and reliance on precise proteome regulation, UPS integrity is indispensable for neuronal survival
Data filtering Quality control was conducted on cells through a filtering process based on three criteria: total unique molecular identifiers (UMIs) per cell, the number of detected genes per cell, and the percentage of mitochondrial gene counts per cell
Anthracycline-based FAC and FEC regimens demonstrate Level 1 evidence through Phase III trials, with GEICAM showing superior disease-free survival in 985 women and EBCTCG meta-analyses confirming 38% mortality reduction in women under 50 years, establishing it as adjuvant standard despite manageable cardiotoxicity