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5 Conclusion Following single and multiple ascending doses, oral semaglutide up to 40 mg was safe and tolerable, with a safety profile as expected for the GLP-1 receptor agonist drug class

Mechanism of Action of GLP-1RAs in Type 2 Diabetes These effects have positioned GLP-1RAs as a cornerstone in the management of type 2 diabetes, particularly in individuals with obesity

Inflammasome inhibition prevents alpha-synuclein pathology and dopaminergic neurodegeneration in mice