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Possible reactions noted in the available literature include headache, mild gastrointestinal discomfort, difficulty sleeping, or mood changes
However, the potential for delaying or preventing the progression of T2DM in patients treated with GIP and GLP-1 remains uncertain, as there is currently no definitive evidence from human studies demonstrating that enhanced incretin activity directly affects -cell mass or alters the progressive loss of insulin secretory capacity in humans
10.1111/exd.12372 Exp
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