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The retarded leaching of nanoclusters can be attributed to their large size in comparison with molecular dyes and it is a clear advantage for imaging purposes as dye leaching decreases the fluorescence brightness of NPs and increases the background signal resulting in unfavorable imaging inefficiency/artifacts 50

Limitations of current studies When considering the limitations, not all studies used the same level of microscopic assessment, however, this is to be expected

Yes, and this is one of the most common reasons oral supplements stop working for people