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2 Thiamine (vitamin B1) and its metabolic significance Thiamine is an essential water-soluble vitamin, naturally occurring in a wide variety of foods

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Moreover, curcumin treatment not only quells oxidative stress in the myocardium but also impedes myocardial inflammation, which improves heart function and decreases heart damage [184,185,186,187,188]

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The current evidence base supports the idea that multi-pronged therapies targeting cellular metabolism, inflammation, and vitamin metabolism simultaneously have the greatest potential for translating into effective treatments for ASD

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