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The authors RC and FP declared that they were an editorial board member of Frontiers at the time of submission

The methylation process is responsible for: Cellular Repair : synthesis of nucleic acids, production & repair of DNA & mRNA Detoxification and Neurotransmistter Production : interconversion of amino acids Healthy Immune System Function : formation & maturation of red blood cells, white blood cells & platelet production The 677T variant is most commonly associated with early heart disease and stroke and the 1298C variant with a variety chronic illnesses, but either anomaly can cause a wide variety of health problems

MTT (5 mg) was placed in a 5 mL EP tube, and PBS buffer (1 mL) added to dissolve the MTT

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