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Sample type considerations Different biological matrices have different detection characteristics: Urine: Most common testing matrix, metabolites accumulate Blood/plasma: Shorter detection windows for most peptides Dried blood spots: Emerging method with good sensitivity Hair: Not commonly used for peptides but theoretically possible Most anti-doping testing uses urine

For most healthy adults, the difference is minimal, because both forms restore B12 levels effectively

While DUL 0.6 mg/kg cause a significant elevation in the relative kidney weight compared to DUL 0.2 mg/kg group, (p=0.0202)

Blood 110 , 21402147 (2007)