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Foods and Habits That Make Side Effects Worse While there is no official dietary restriction list for semaglutide, clinical experience consistently identifies these as common triggers for worsened GI symptoms: High-fat foods: fried foods, fast food, heavy creamy sauces Very sugary foods and drinks Carbonated beverages (increase bloating and gas) Alcohol (worsens nausea and GI irritation

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When used for weight management, it is administered at a higher dose than when used for diabetes treatment