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While there are a few studies that demonstrate potential influences of these compounds on blood sugar and weight, the evidence is far from conclusive or robust, says Martin Binks, PhD, a professor and the chair of the Department of Nutrition and Food Studies at the George Mason University College of Public Health

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Experimental studies have demonstrated that chronic hyperglycemia may reduce -cell expression of GLP-1 receptors, leading to diminished responsiveness to endogenous GLP-1 [7, 10]

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