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Out of control vomiting that inhibits drinking or even eating
Source: The steepest loss often shows up after you reach a maintenance dose, which many people hit around Week 20 for the injection (STEP 4 maintenance trial, JAMA)
Patients with certain medical conditions, those who experienced severe side effects on lower doses, or those who havent followed the proper dose escalation schedule wont be candidates for 7.2mg
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