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These limitations do not invalidate the published model studies
It is also involved in a series of physiological processes such as anti-tumor responses, control inflammation, and immune system homeostasis ( A team studied the immune responses of 54 COVID-19 patients and found that TNF- and IL-6 production by circulating monocytes was sustained
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(4) Macro-B12 becomes a reasonable consideration when a value is very high, persists over time, comes with no B12 exposure, sits alongside an unrevealing workup, or disagrees with functional markers
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