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[9] Although it has historically been positioned as a salvage therapy, IT therapy is now being considered earlier in the treatment spectrum
In other studies in a limited number of patients with advanced cancer, the distribution half-life averaged 17-85 min and the terminal elimination half-life averaged 2.6-15 hr following single iv doses of 0.1 or 0.25 mg/kg of pentostatin
Whats more, the study only tested treatment for approximately two months
The body has enzymes that convert most GSSG back into the active GSH form, continuously replenishing the supply
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