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Cytokine Modulation Pro-inflammatory cytokines like TNF-alpha, IL-6, and IL-1beta drive the inflammatory cascade that causes pain, swelling, and tissue damage
Due to its historical association with anaemia, it is common for medical doctors to screen indirectly for B12 deficiency via a full blood count, looking for megaloblastic anaemia (raised mean cell volume MCV/macrocytosis)
The research gap isnt scientific skepticism its economics
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