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It was reported that GLP-1 (9-36) decreased the level of nuclear factor kappa-B (NF-B) in astrocytes after oxygen-glucose deprivation/reoxygenation (OGD/R) damage and inhibited neuronal apoptosis around the infarct area against CIR, the mechanism of which might be relying on the activation of the IGF-1 receptor rather than the GLP-1 receptor ( Exenatide Exenatide (Byetta and Bydureon, AstraZeneca), originally discovered as Exendin-4 (Ex-4) in the saliva of the gila monster (Heloderma suspectum), is a synthetic peptide with 39 amino acids (129)

Oral BPC-157 Peptide Therapy fills the role none of these other treatments can: sustained, systemic daily healing support

PMC 5696016

doi: 10.1096/fj.07-8560rev 116 ZuoSYuJPanHLuL