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These drugs are designed for diabetes and weight loss, not fertility, but the metabolic changes they create can have powerful ripple effects on reproductive health
The tested animals that were listed in the patent include rats, mice, rabbits, guinea pigs and pigs, as well as a single study in humans
On the other hand, it might also reflect a new steady state in which bone turnover is suppressed with long-term energy depletion, not unlike the skeletal changes in mice with CR
A possible reason for this is that there is a higher background concentration of carnitine in muscle than in the liver, or that the degree of supplementation with l- and d-carnitine was insufficient to significantly alter the concentration of acyl-carnitine, such that any change in lipid metabolism in muscle was not obvious
