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Benefits & How It Works is a useful companion read
Septerna has developed a native complex platform that can reconstitute the GLP-1 receptor within an artificial lipid bilayer, complexed with combinations of drug and internal cell signalling molecules, which replicates the dynamics of the signalling process at scale
As replacements that 'mimic' or 'boost' GLP-1 on their own, the effect is far weaker than the medication and the big claims are mostly marketing
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