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Clinical medicine (London, England), 23 (4), 284291
As a GLP-1 receptor agonist, semaglutide works by mimicking the incretin hormone GLP-1
It binds to melanocortin receptors (primarily MC1R) and stimulates melanogenesis the production of melanin in the skin
The recognised conditions are type 2 diabetes, prediabetes, high blood pressure, high cholesterol or dyslipidaemia (an unhealthy balance of fats in the blood), cardiovascular disease, and obstructive sleep apnoea 1,2
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