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Cross-sectional studies have shown that plasma and tissue glutathione concentrations decrease by approximately 10-15% per decade after age 45, and this decline is accelerated in conditions associated with chronic oxidative stress, including type 2 diabetes, cardiovascular disease, neurodegenerative diseases, HIV/AIDS, chronic liver disease, and chronic obstructive pulmonary disease (COPD) [2][3][10][11]
Durante el proceso natural de envejecimiento, se producen cambios en el cuerpo: la piel empieza a perder su brillo y se vuelve ms flcida, arrugada y pigmentada
When donating an electron, glutathione itself becomes reactive and readily reacts with another reactive glutathione to form GSSG
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