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It is important to note that patients with a history of major depression were actually excluded from the phase 3 randomized controlled trials (RCTs) of these medications 10,11,12,13,14,15,21,22,23
These transporters pump conjugates into bile (for intestinal excretion) or blood (for renal excretion)
J Neuroimmunol 207:111116 Vargas DL, Nascimbene C, Krishnan C, Zimmerman AW, Pardo CA (2005) Neuroglial activation and neuroinflammation in the brain of patients with autism
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