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Since the first GLP-1 agonist was approved in 2005, a succession of new compounds has hit the market every few years
People with certain medical conditions shouldnt take it
Precision genetic testing can identify these predispositions before starting therapy, allowing clinicians to customize starting doses and escalation schedules
Media coverage and celebrity adoption accelerated public awareness, though it also led to off-label use and supply chain stress that affected patients with genuine medical need
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