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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR

In the SURPASS and SURMOUNT trials, nausea was reported in up to 32% of participants, diarrhea in 23%, vomiting in 12%, and constipation in 11%

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Improved Metabolic Health In addition to weight loss, GLP-1 medications may help improve several metabolic health markers, including: Blood sugar levels HbA1c Blood pressure Triglycerides These benefits may be especially valuable for patients managing pre-diabetes or metabolic syndrome