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579 This staining combination provides two key insights: a mosaic pattern of SDH-positive but COX-negative fibers indicates an mtDNA defect involving COX, while a mosaic pattern of both SDH-positive and COX-positive fibers suggests an mtDNA defect involving NADH dehydrogenase (respiratory complex I) or cytochrome c reductase (respiratory complex III)
The combination outperformed both individual agents by a meaningful margin, and 60% of participants on the combination lost at least 20% of their body weight
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Skin brightening becomes visible after 46 sessions, with best results seen after 812 sessions
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