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When collagen is broken down (for instance during injury), GHK is released and can bind copper
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Furthermore, several inhibitors (e.g., DC-TEADin02 and K-975) that target the autopalmitoylation pocket of the TEA domain (TEAD) of transcription factors occupy this hydrophobic cavity, where they competitively inhibit TEAD autopalmitoylation and consequently disrupt its oncogenic transcriptional activity [187, 188]
These serious complications, while uncommon, highlight the importance of proper screening before treatment
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