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The neutralization titers were defined as the highest serum dilution that protected 50% the cell cultures from CPE
Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris
doi: 10.3390/cells8070657 6 ConigliaroPChimentiMSTriggianesePSunziniFNovelliLPerriconeCet al
Mechanistically, the mitogenic effect promoted by HGF in SVZ cells is dependent on the activation of the ERK pathway ( Previous reports in the context of SCI recovery reported a positive effect of HGF in the promotion of grafted NSC differentiation and synapse formation between new neurons and the descending cortico-spinal fibers ( Neural stem cell differentiation into astrocytes and, at a lower extent, into new neurons is regulated by some factors such as bone marrow proteins (BMPs), whose expression is upregulated in the injury lesion after SCI ( in vitro similarly to BMSCs and in a dose-dependent fashion
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