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The resulting increase in intracellular NAD+ availability activates sirtuins particularly SIRT1, which regulates insulin sensitivity, gluconeogenesis, cholesterol synthesis, and fatty acid oxidation, and SIRT3, which governs mitochondrial antioxidant defences and energy metabolism
Gout: epidemiology and lifestyle choices
doi: 10.9758/cpn.2015.13.2.129 157 EkinciGNSanlierN
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