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GLP-1 neurons in the nucleus tractus solitarius widely project to the central nervous system, including the hypothalamus (paraventricular nucleus, supraoptic nucleus, arcuate nucleus, and hypothalamic dorsomedial nucleus), brainstem (parabrachial nucleus, reticular formation, dorsal vagal nucleus), thalamus, and intermedio-lateral cell column
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Increased demand for NAD+ relative to ATP drives aerobic glycolysis
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