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To improve the stability of CPPs, replacement of L-amino acids with D-variants or unnatural amino acids and PEGylation can be considered (Wang et al., 2022)
Floaters or color change: stop and toss it those are degradation signals, not cosmetic
As expected, and consistent with a reduced interaction of the amidated C-terminal tyrosine with the CTR ECD, CagriP37Y presented a lower potency than Cagri in cells expressing CTR alone (Supplementary Fig
Neural Regen Res, 2022
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