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P53 phosphorylation at Ser15 enhances the affinity of both FOXO4 and FOXO4-DRI for p53 TAD2 explaining the preferential engagement of FOXO4-DRI with the hyperphosphorylated p53 characteristic of senescent cells
This interaction stimulates collagen production, which is vital for maintaining skin elasticity and firmness (1)
Korean drugmaker wins $100 million milestone, 90% revenue share over 10 years in exclusive US oral semaglutide supply and commercialization agreement
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