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The copper ion binds to the peptide through a square-planar pyramid configuration, creating an extraordinarily stable complex with a binding affinity (pK = 16.44) approximately 10 million times higher than other tripeptides

Practical Guidance (Interim) Clinicians should counsel that current evidence does not justify routine therapeutic use outside registered ethically approved research protocols and that online sourcing introduces quality, legal and professional risk

Low levels can contribute to brain fog, irritability, and even mild depression