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In the allocation concealment bias, 10 (29.4%) studies and 1 (2.9%) study were classified as unclear and high risk because they were not reported, and an open random allocation table was used
CARDIOVASCULAR HEALTH Cardiac Function Ejection fraction: improvement of 1015% in heart failure models Wall thickness VI: increase in functional myocardial mass 8% Diastolic function: E/A ratio improvement Exercise capacity: increase in VO max 12-18% Cardiovascular Metabolism Lipid profile: LDL 1015%, HDL 812% Endothelial function: improves endothelium-dependent vasodilation 25% Arterial stiffness: reduced pulse wave velocity 10% Blood pressure: systolic decrease 5-8 mmHg 5
Private GLP-1 treatment costs 150300 monthly for medication alone (1,8003,600 annually), plus 50200 per consultation, compared to approximately 119 annually on NHS prescription in England (or free with exemption)
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