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The critical safety concern is not reduced fertility but rather the potential for pregnancy during treatment
Published Research (Scientific Record) Foundational Mechanism 2003 Original PT-141 mechanism / clinical entry paper Molinoff, Shadiack, Earle, Diamond, and Quon described PT-141 as a synthetic peptide analogue of -MSH that is an agonist at MC3R and MC4R, expressed primarily in the central nervous system
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Pancreatic amylin as a centrally acting satiating hormone
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