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Research has found that Glaucocalyxin A can significantly improve liver fibrosis in HF mice by increasing the abundance of Muribaculaceae and Bacteroidaceae, reducing levels of AST, ALT, total bile acid (TBA), and inflammatory markers (IL-1, TNF-), ameliorating hepatic pathological damage and collagen deposition, and lowering apoptosis levels [161]
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Patients who receive GLP-1 prescriptions without concurrent metabolic and hormonal evaluation tend to regain weight after stopping because the underlying physiological drivers have not been addressed
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