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First improvement at 1 to 2 weeks, significant change by week 4
Pierwsze badania przeprowadzono w latach dziewidziesitych na Uniwersytecie w Zagrzebiu przez grup badawcz profesora Predraga Sikicia
Subsequent mass spectrometry analysis identified interacting proteins, with AFG3-like matrix AAA peptidase subunit 2 (AFG3L2), a mitochondrial inner membrane m-AAA protease, highlighted as a key interactor
This work supports the possibility that there may not be any additional direct mRNA transcriptional targets of GLP-1 signaling
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