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Semaglutide (Ozempic, Wegovy, Rybelsus) is a GLP-1 receptor agonist that works by mimicking natural hormones to regulate blood sugar and reduce appetite
This mechanistic hypothesis underpins the substantial weight loss signals observed in early trials, though the precise contribution of each receptor pathway in humans remains an active area of investigation
We propose that mental GLP-1RAs modify nicotine-induced effects on the mesolimbic dopamine system and consequently decreasing nicotine intake
Avery, M
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