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Supplementation in high doses (over 1000 mg) relatively shortly before training appears to be advisable, as circulating L-carnitine - in contrast to muscle carnitine - presumably has a vascular-protective effect against oxidative damage in the microvascular area

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Health Benefits of L-Carnitine Beyond performance, L-carnitine offers various health benefits: Metabolic Health Studies have demonstrated that L-carnitine supplementation can lower levels of small, dense LDL particles associated with atherosclerosis and improve glucose metabolism by enhancing mitochondrial efflux of excess acyl groups, which stimulates glucose oxidation and reduces fatty acid oxidation

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