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For significant weight loss, prescription GLP-1 medications like semaglutide and tirzepatide have the strongest evidence
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The SURPASS-1 trial investigated the efficacy and safety of the three doses of 5, 10, or 15 mg tirzepatide in drug-nave patients with T2D who were not sufficiently controlled with a lifestyle intervention with diet and exercise versus placebo (70)
Zepbound (tirzepatide) Another effective option offered at Klinic, Zepbound, targets both GLP-1 and GIP receptors, promising unprecedented weight loss results
