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Pharmacokinetic Interactions: Pharmacokinetic interactions involve changes in absorption, distribution, metabolism, or elimination of a drug
[2] [7] These effects typically diminish over time but can be pronounced during the initial weeks of treatment or following dose increases
In the liver, retatrutide has similar efficacy to naturally occurring glucagon
In the gut, they decrease secretion of ghrelin (the hunger hormone) and increase peptide YY and cholecystokinin levels
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