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Other studies have explored the role of estrogen in protecting from ROS [116] and cellular senescence [117]
It downregulated ACSL4 and CD71 expression, significantly increased the expression of System Xc , GPX4, and Ferritin, reduced ROS levels, and inhibited ferroptosis, inflammatory responses, and mitochondrial dysfunction in BV2 cells
Flavonoids were quantified using peak areas of A 280nm , A 500nm or selective ion monitoring in positive mode with external calibration curves prepared in the same solvent as the samples
Ghigo, E., Arvat, E., Gianotti, L., Imbimbo, B
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