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239 This cascade promotes the secretion of immunosuppressive cytokines such as TGF-, recruitment of T regs and M2 macrophages, and suppression of CD8 T and NK cell cytotoxicity, ultimately facilitating metastasis and immune resistance
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This induces the activation of microglia and astrocytes, which in turn aggravates neurodegenerative damage and drives the progression of Alzheimers disease (AD) (Wang et al., 2023)
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