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Regulatory guidelines for the analysis of therapeutic peptides and proteins

This pharmacokinetic property determines how often a peptide needs to be administered to maintain therapeutic levels

and is useful in some cases of allergies by virtue of its ability to reduce histamine release.123 One of the sulfur-containing amino acids (along with cysteine and cystine), methionine is important (essential) to many bodily functions and must be directly consumed through supplementation or methionine-containing proteins

Overall, both X(GD_L)f and X(GD) exhibit more stringent substrate requirements than wild-type BoNT/X protease or X(PC)