In contrast, the heart is relatively simple, and there are multiple randomized trials that show that GLP-1 drugs, as well as some other drugs for diabetes, such as the SGLT2 inhibitors, pioglitazone, and metformin, reduce the risk for cardiovascular disease in people with diabetes
The synergistic engagement of these pathways results in broader metabolic benefits than those achieved through single receptor targeting alone, offering a more physiologic and integrated approach to metabolic regulation
The study published in JAMA Psychiatry found that patients with alcohol use disorder (AUD) who were prescribed GLP-1 drugs, popularly known by their brand names Ozempic and Wegovy, had a significantly lower risk of hospitalization for alcohol-related issues
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