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Risk Factors: High doses (2000mg+ daily) Long-term continuous use (6+ months) Pre-existing liver conditions Alcohol consumption use Symptoms to Watch: Unusual fatigue weakness Yellowing of skin/eyes (jaundice) Dark urine color Severe abdominal pain Loss of appetite 2
Safety and efficacy have not been established in patients younger than 18 years
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Essentially, endurance athletes may need to override their dulled thirst mechanism to avoid performance-limiting dehydration
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