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64,65 In particular, because CKD contributes to the progression of cardiovascular disease through many pathways, the authors of a 2021 review published in Circulation stated that CKD mimics an accelerated aging of the cardiovascular system. 66 Blood Clot and Bleeding Risks Chronic kidney disease increases the risk of bleeding events as well as blood clots (thrombosis) and related health problems
In fibroblast cultures, biochemical assays show increased cell migration, enhanced cytoskeletal organization, and improved survival under oxidative stress conditions
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