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Methods The study protocol was registered in PROSPERO (CRD420251002447)

It is sold as a lyophilized powder for research use , and this page documents how such a vial is reconstituted and handled

In our matched analysis of 555 patients in each group, starting a GLP-1 RA within 6 months of IIH diagnosis was associated with fewer symptoms/signs (including headaches, visual disturbance/blindness, and papilledema), fewer procedures, less medication use, and lower all-cause mortality at 1 year

This dosage was also used in the phase-3 trials which led to the FDA approval of 1.75 mg bremelanotide injections for premenopausal women with HSDD