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According to clinical observations reported by Integrative Medicine of Los Angeles, an intramuscular B12 injection is absorbed more slowly over a longer time frame compared to an IV infusion, which delivers the nutrient immediately into the vasculature
Moreover, enzymes (alcohol dehydrogenase 1, aldehyde dehydrogenase 2, and cytochrome P450 2E1) and regulators (farnesoid X receptor) involved in alcohol metabolism were markedly increased in APP/PS1 mice treated with alcohol compared to WT controls, indicating dysregulated alcohol metabolism
or were fed DOX-supplemented chow (200mg/kg) or chow-alone for 48 hrs