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As glucose rises and falls more sharply, hunger signals tend to build through the afternoon and evening
That means it activates GLP-1 receptors involved in appetite, insulin response, and digestion
They do not address these secondary clinical considerations directly
Glycemic efficacy and safety of glucagon-like peptide-1 receptor agonist on top of sodium-glucose co-transporter-2 inhibitor treatment compared to sodium-glucose co-transporter-2 inhibitor alone: A systematic review and meta-analysis of randomized controlled trials
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